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Arhgef15 (NM_177566) Mouse Recombinant Protein

Product Specifications

Background

Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse Rho guanine nucleotide exchange factor (GEF) 15 (Arhgef15), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

D130071N09; D530030K12Rik; E5

Gene ID

442801

UniProt

Q5FWH6

Accession Number mRNA

NM_177566

Chromosomal Location

11 B3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

92.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Arhgef15

Species

Mouse

Protein ID

NP_808234

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/442801

Uniprot URL

https://www.uniprot.org/uniprot/Q5FWH6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_177566

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_808234

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