Arhgef15 (NM_177566) Mouse Recombinant Protein
Product Specifications
Background
Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Rho guanine nucleotide exchange factor (GEF) 15 (Arhgef15), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
D130071N09; D530030K12Rik; E5
Gene ID
442801
UniProt
Q5FWH6
Accession Number mRNA
NM_177566
Chromosomal Location
11 B3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
92.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Arhgef15
Species
Mouse
Protein ID
NP_808234
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/442801
Uniprot URL
https://www.uniprot.org/uniprot/Q5FWH6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177566
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_808234
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