Arhgef15 (NM_177566) Mouse Recombinant Protein
Selected Variant
PM44966M5
Size: 20 µg
Product Specifications
Background
Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse Rho guanine nucleotide exchange factor (GEF) 15 (Arhgef15), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
D130071N09; D530030K12Rik; E5
Gene ID
442801
UniProt
Q5FWH6
Accession Number mRNA
NM_177566
Chromosomal Location
11 B3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
92.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Arhgef15
Species
Mouse
Protein ID
NP_808234
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/442801
Uniprot URL
https://www.uniprot.org/uniprot/Q5FWH6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177566
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_808234
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