Vps39 (NM_178851) Mouse Recombinant Protein
Selected Variant
PM44937M5
Size: 20 µg
Product Specifications
Background
May play a role in clustering and fusion of late endosomes and lysosomes (By similarity) . Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse VPS39 HOPS complex subunit (Vps39), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
A230065P22Rik; AW743070; mVam6; Vam6; Vam6P
Gene ID
269338
UniProt
Q8R5L3, Q5KU38
Accession Number mRNA
NM_178851
Chromosomal Location
2 E5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
101.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Vps39
Species
Mouse
Protein ID
NP_849182
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/269338
Uniprot URL
https://www.uniprot.org/uniprot/Q8R5L3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_178851
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_849182
Price
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