Hkdc1 (NM_145419) Mouse Recombinant Protein

Product Specifications

Background

Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases (By similarity) . Has low glucose phosphorylating activity compared to other hexokinases (By similarity) . Involved in glucose homeostasis and hepatic lipid accumulation (PubMed:30543855) . Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role (PubMed:25648650, PubMed:27459389) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse hexokinase domain containing 1 (Hkdc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

BC016235

Gene ID

216019

UniProt

Q91W97

Accession Number mRNA

NM_145419

Chromosomal Location

10 B4

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

102.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.