Lpin1 (NM_015763) Mouse Recombinant Protein
Product Specifications
Background
Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.[UniProtKB/Swiss-Prot Function]
Synonyms
4631420P06; fld; Kiaa0188; Lipin1; mKIAA0188
Gene ID
14245
UniProt
Q91ZP3, E9QKQ5
Accession Number mRNA
NM_015763
Chromosomal Location
12 7.9 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
102.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Lpin1
Species
Mouse
Protein ID
NP_056578
Overview
Purified recombinant protein of Mouse lipin 1 (Lpin1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14245
Uniprot URL
https://www.uniprot.org/uniprot/Q91ZP3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015763
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056578
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