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Ints5 (NM_176843) Mouse Recombinant Protein

Selected Variant

PM44818M5

Size: 20 µg

Product Specifications

Background

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse integrator complex subunit 5 (Ints5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1110055N21Rik; mKIAA1698

Gene ID

109077

UniProt

Q8CHT3

Accession Number mRNA

NM_176843

Chromosomal Location

19 A

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

108.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Ints5

Species

Mouse

Protein ID

NP_789813

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/109077

Uniprot URL

https://www.uniprot.org/uniprot/Q8CHT3

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_176843

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_789813

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