Kdm4c (NM_144787) Mouse Recombinant Protein
Product Specifications
Background
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
2410141F18Rik; AA517467; Gasc1; Jmjd2c
Gene ID
76804
UniProt
Q8VCD7, A2BEG5
Accession Number mRNA
NM_144787
Chromosomal Location
4 C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
120.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Kdm4c
Species
Mouse
Protein ID
NP_659036
Overview
Purified recombinant protein of Mouse lysine (K) -specific demethylase 4C (Kdm4c), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/76804
Uniprot URL
https://www.uniprot.org/uniprot/Q8VCD7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_144787
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_659036
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