Smc6 (NM_025695) Mouse Recombinant Protein
Product Specifications
Background
Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse structural maintenance of chromosomes 6 (Smc6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2810489L22Rik; 3830418C19Rik; AA990493; AU018782; AW742439; mKIAA4103; SMC-6; Smc6l1
Gene ID
67241
UniProt
Q924W5
Accession Number mRNA
NM_025695
Chromosomal Location
12 A1.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
127.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Smc6
Species
Mouse
Protein ID
NP_079971
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67241
Uniprot URL
https://www.uniprot.org/uniprot/Q924W5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025695
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079971
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