Plcg1 (NM_021280) Mouse Recombinant Protein

Product Specifications

Background

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse phospholipase C, gamma 1 (Plcg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI894140; Cded; Plc-1; Plc-gamma1; Plcg-1

Gene ID

18803

UniProt

Q62077

Accession Number mRNA

NM_021280

Chromosomal Location

2 80.97 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

150.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.