Plcg1 (NM_021280) Mouse Recombinant Protein
Product Specifications
Background
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse phospholipase C, gamma 1 (Plcg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI894140; Cded; Plc-1; Plc-gamma1; Plcg-1
Gene ID
18803
UniProt
Q62077
Accession Number mRNA
NM_021280
Chromosomal Location
2 80.97 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
150.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Plcg1
Species
Mouse
Protein ID
NP_067255
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18803
Uniprot URL
https://www.uniprot.org/uniprot/Q62077
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021280
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_067255
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