Lamtor4 (NM_001081108) Mouse Recombinant Protein
Selected Variant
PM44633M5
Size: 20 µg
Product Specifications
Background
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 (Lamtor4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
0910001L09Rik; AV006840
Gene ID
66096
UniProt
Q8CF66
Accession Number mRNA
NM_001081108
Chromosomal Location
5 G2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
11.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Lamtor4
Species
Mouse
Protein ID
NP_001074577
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66096
Uniprot URL
https://www.uniprot.org/uniprot/Q8CF66
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001081108
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001074577
Price
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