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Lamtor4 (NM_001081108) Mouse Recombinant Protein

Selected Variant

PM44633M5

Size: 20 µg

Product Specifications

Background

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 (Lamtor4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

0910001L09Rik; AV006840

Gene ID

66096

UniProt

Q8CF66

Accession Number mRNA

NM_001081108

Chromosomal Location

5 G2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

11.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Lamtor4

Species

Mouse

Protein ID

NP_001074577

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/66096

Uniprot URL

https://www.uniprot.org/uniprot/Q8CF66

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001081108

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001074577

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