Mcrip1 (NM_001033231) Mouse Recombinant Protein
Product Specifications
Background
The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP (s) . When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP (s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse MAPK regulated corepressor interacting protein 1 (Mcrip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Fam195b; Mcrip1
Gene ID
192173
UniProt
Q3UGS4
Accession Number mRNA
NM_001033231
Chromosomal Location
11 E2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
11.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mcrip1
Species
Mouse
Protein ID
NP_001028403
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/192173
Uniprot URL
https://www.uniprot.org/uniprot/Q3UGS4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001033231
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001028403
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