Catsperz (NM_001039494) Mouse Recombinant Protein

Product Specifications

Background

Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation (PubMed:28226241, PubMed:31056283) . Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (PubMed:28226241, PubMed:31056283) . Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract (PubMed:28226241) . Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel (PubMed:31056283) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse cation channel sperm associated auxiliary subunit zeta (Catsperz), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1700019N12Rik; A430107B04Rik; MLZ-622

Gene ID

67077

UniProt

Q9CQP8

Accession Number mRNA

NM_001039494

Chromosomal Location

19 A

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

22.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.