Drc1 (NM_001033460) Mouse Recombinant Protein
Product Specifications
Background
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.[UniProtKB/Swiss-Prot Function]
Synonyms
B2b1654Clo; Ccdc164; Gm1060
Gene ID
381738
UniProt
Q3USS3
Accession Number mRNA
NM_001033460
Chromosomal Location
5 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
88.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Drc1
Species
Mouse
Protein ID
NP_001028632
Overview
Purified recombinant protein of Mouse dynein regulatory complex subunit 1 (Drc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/381738
Uniprot URL
https://www.uniprot.org/uniprot/Q3USS3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001033460
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001028632
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