Spindoc (NM_001167831) Mouse Recombinant Protein
Product Specifications
Background
Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway (PubMed:29061846) . Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4 (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse spindlin interactor and repressor of chromatin binding (Spindoc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1700105P06Rik; AI846148; SPIN-DOC
Gene ID
68229
UniProt
Q05AH6
Accession Number mRNA
NM_001167831
Chromosomal Location
19 A
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
34.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Spindoc
Species
Mouse
Protein ID
NP_001161303
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/68229
Uniprot URL
https://www.uniprot.org/uniprot/Q05AH6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001167831
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001161303
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