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Apoo (NM_026673) Mouse Recombinant Protein

Product Specifications

Background

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (By similarity) . Can induce cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151) . Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP) -dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (By similarity) .[UniProtKB/Swiss-Prot Function]

Synonyms

0610008C08Rik; 1110019O03Rik

Gene ID

68316

UniProt

Q9DCZ4

Accession Number mRNA

NM_026673

Chromosomal Location

X C3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

22.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Apoo

Species

Mouse

Protein ID

NP_080949

Overview

Purified recombinant protein of Mouse apolipoprotein O (Apoo), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/68316

Uniprot URL

https://www.uniprot.org/uniprot/Q9DCZ4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_026673

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_080949

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