Khdc3 (NM_025890) Mouse Recombinant Protein

Product Specifications

Background

Required for maintenance of euploidy during cleavage-stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function. Capable of binding RNA.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse KH domain containing 3, subcortical maternal complex member (Khdc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2410004A20Rik; AI467128; FILIA; OEEP48

Gene ID

66991

UniProt

Q9CWU5

Accession Number mRNA

NM_025890

Chromosomal Location

9 D

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

48 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.