Khdc3 (NM_025890) Mouse Recombinant Protein
Product Specifications
Background
Required for maintenance of euploidy during cleavage-stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function. Capable of binding RNA.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse KH domain containing 3, subcortical maternal complex member (Khdc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2410004A20Rik; AI467128; FILIA; OEEP48
Gene ID
66991
UniProt
Q9CWU5
Accession Number mRNA
NM_025890
Chromosomal Location
9 D
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
48 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Khdc3
Species
Mouse
Protein ID
NP_080166
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66991
Uniprot URL
https://www.uniprot.org/uniprot/Q9CWU5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025890
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080166
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