Tle2 (NM_019725) Mouse Recombinant Protein
Product Specifications
Background
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse transducin-like enhancer of split 2 (Tle2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Grg2; mKIAA4188
Gene ID
21886
UniProt
Q9WVB2, Q3UN01
Accession Number mRNA
NM_019725
Chromosomal Location
10 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
83.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tle2
Species
Mouse
Protein ID
NP_062699
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/21886
Uniprot URL
https://www.uniprot.org/uniprot/Q9WVB2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019725
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062699
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