Cln5 (NM_001033242) Mouse Recombinant Protein

Product Specifications

Background

Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse ceroid-lipofuscinosis, neuronal 5 (Cln5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

A730075N08Rik

Gene ID

211286

UniProt

Q3UMW8, B2RUP8

Accession Number mRNA

NM_001033242

Chromosomal Location

14 51.71 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

39.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.