Asxl1 (NM_001039939) Mouse Recombinant Protein

Product Specifications

Background

Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG) . Acts as a coactivator of RARA and RXRA through association with NCOA1. Acts as a corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse additional sex combs like 1 (Asxl1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

MKIAA0978

Gene ID

228790

UniProt

P59598, Q24JP2

Accession Number mRNA

NM_001039939

Chromosomal Location

2 H1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

163.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.