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Adam11 (NM_009613) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. The protein encoded by this gene is believed to lack metalloproteinase activity due to the lack of a critical catalytic motif. Mice lacking the encoded protein exhibit defects in spatial learning, motor coordination and altered perception of pain. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing. [provided by RefSeq, May 2016]

Overview

Purified recombinant protein of Mouse a disintegrin and metallopeptidase domain 11 (Adam11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AW060611; Mdc

Gene ID

11488

UniProt

Q9R1V4, Q7TQG7, Q3TZE2

Accession Number mRNA

NM_009613

Chromosomal Location

11 66.48 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

84.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Adam11

Species

Mouse

Protein ID

NP_033743

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11488

Uniprot URL

https://www.uniprot.org/uniprot/Q9R1V4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_009613

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_033743

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