Adam11 (NM_009613) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. The protein encoded by this gene is believed to lack metalloproteinase activity due to the lack of a critical catalytic motif. Mice lacking the encoded protein exhibit defects in spatial learning, motor coordination and altered perception of pain. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing. [provided by RefSeq, May 2016]
Synonyms
AW060611; Mdc
Gene ID
11488
UniProt
Q9R1V4, Q7TQG7, Q3TZE2
Accession Number mRNA
NM_009613
Chromosomal Location
11 66.48 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
84.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Adam11
Species
Mouse
Protein ID
NP_033743
Overview
Purified recombinant protein of Mouse a disintegrin and metallopeptidase domain 11 (Adam11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11488
Uniprot URL
https://www.uniprot.org/uniprot/Q9R1V4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009613
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033743
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