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Nek9 (NM_145138) Mouse Recombinant Protein

Product Specifications

Background

Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse NIMA (never in mitosis gene a) -related expressed kinase 9 (Nek9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

C130021H08Rik

Gene ID

217718

UniProt

Q8K1R7, Q69Z43

Accession Number mRNA

NM_145138

Chromosomal Location

12 D1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

107.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Nek9

Species

Mouse

Protein ID

NP_660120

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/217718

Uniprot URL

https://www.uniprot.org/uniprot/Q8K1R7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_145138

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_660120

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