Nek9 (NM_145138) Mouse Recombinant Protein
Product Specifications
Background
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse NIMA (never in mitosis gene a) -related expressed kinase 9 (Nek9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
C130021H08Rik
Gene ID
217718
UniProt
Q8K1R7, Q69Z43
Accession Number mRNA
NM_145138
Chromosomal Location
12 D1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
107.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nek9
Species
Mouse
Protein ID
NP_660120
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/217718
Uniprot URL
https://www.uniprot.org/uniprot/Q8K1R7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145138
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_660120
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