Sorbs2 (NM_172752) Mouse Recombinant Protein

Product Specifications

Background

Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 (By similarity) . May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse sorbin and SH3 domain containing 2 (Sorbs2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2010203O03Rik; 9430041O17Rik; A530071H08; Argbp2; mKIAA0777; nArgBP2

Gene ID

234214

UniProt

B7ZWM6

Accession Number mRNA

NM_172752

Chromosomal Location

8 B1.1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

134.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.