Plscr3 (NM_001168497) Mouse Recombinant Protein
Product Specifications
Background
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.[UniProtKB/Swiss-Prot Function]
Synonyms
2210403O21Rik; 2610037N06Rik; ESTM3; X83310
Gene ID
70310
UniProt
Q9JIZ9, Q5F283
Accession Number mRNA
NM_001168497
Chromosomal Location
11 42.9 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
31.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Plscr3
Species
Mouse
Protein ID
NP_001161969
Overview
Purified recombinant protein of Mouse phospholipid scramblase 3 (Plscr3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/70310
Uniprot URL
https://www.uniprot.org/uniprot/Q9JIZ9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001168497
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001161969
Curated Selection
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