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Nkrf (NM_029891) Mouse Recombinant Protein

Product Specifications

Background

Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription (By similarity) .[UniProtKB/Swiss-Prot Function]

Synonyms

9430034D17Rik; AW124770; C80287

Gene ID

77286

UniProt

Q8BY02

Accession Number mRNA

NM_029891

Chromosomal Location

X A3.3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

77.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Nkrf

Species

Mouse

Protein ID

NP_084167

Overview

Purified recombinant protein of Mouse NF-kappaB repressing factor (Nkrf), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/77286

Uniprot URL

https://www.uniprot.org/uniprot/Q8BY02

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_029891

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_084167

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