Nkrf (NM_029891) Mouse Recombinant Protein
Product Specifications
Background
Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse NF-kappaB repressing factor (Nkrf), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
9430034D17Rik; AW124770; C80287
Gene ID
77286
UniProt
Q8BY02
Accession Number mRNA
NM_029891
Chromosomal Location
X A3.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
77.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nkrf
Species
Mouse
Protein ID
NP_084167
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/77286
Uniprot URL
https://www.uniprot.org/uniprot/Q8BY02
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_029891
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_084167
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