March2 (NM_145486) Mouse Recombinant Protein
Product Specifications
Background
E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.[UniProtKB/Swiss-Prot Function]
Synonyms
9530046H09Rik; MARCH-II
Gene ID
224703
UniProt
Q8CA25
Accession Number mRNA
NM_145486
Chromosomal Location
17 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
31.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
44622
Species
Mouse
Protein ID
NP_663461
Overview
Purified recombinant protein of Mouse membrane-associated ring finger (C3HC4) 2 (March2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/224703
Uniprot URL
https://www.uniprot.org/uniprot/Q8CA25
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145486
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_663461
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