Acvr1c (NM_001033369) Mouse Recombinant Protein

Product Specifications

Background

Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse activin A receptor, type IC (Acvr1c), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

ACTR-IC; ACVRLK7; Alk-7; ALK7; C230097P10

Gene ID

269275

UniProt

Q3V348

Accession Number mRNA

NM_001033369

Chromosomal Location

2 C1.1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

41.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.