Mysm1 (NM_177239) Mouse Recombinant Protein
Product Specifications
Background
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR) -induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse myb-like, SWIRM and MPN domains 1 (Mysm1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
C130067A03Rik; C530050H10Rik
Gene ID
320713
UniProt
Q69Z66
Accession Number mRNA
NM_177239
Chromosomal Location
4 C5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
93.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mysm1
Species
Mouse
Protein ID
NP_796213
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/320713
Uniprot URL
https://www.uniprot.org/uniprot/Q69Z66
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177239
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_796213
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