Fnip2 (NM_001162999) Mouse Recombinant Protein
Product Specifications
Background
Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1 (By similarity) . May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (PubMed:19137017) .[UniProtKB/Swiss-Prot Function]
Synonyms
D630023B12Rik; mKIAA1450
Gene ID
329679
UniProt
Q80TD3
Accession Number mRNA
NM_001162999
Chromosomal Location
3 E3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
122.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Fnip2
Species
Mouse
Protein ID
NP_001156471
Overview
Purified recombinant protein of Mouse folliculin interacting protein 2 (Fnip2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/329679
Uniprot URL
https://www.uniprot.org/uniprot/Q80TD3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001162999
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001156471
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