Fnip2 (NM_001162999) Mouse Recombinant Protein

Product Specifications

Background

Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1 (By similarity) . May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (PubMed:19137017) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse folliculin interacting protein 2 (Fnip2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

D630023B12Rik; mKIAA1450

Gene ID

329679

UniProt

Q80TD3

Accession Number mRNA

NM_001162999

Chromosomal Location

3 E3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

122.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.