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Gp2 (NM_025989) Mouse Recombinant Protein

Product Specifications

Background

Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participates to the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.[UniProtKB/Swiss-Prot Function]

Synonyms

2310037I18Rik; AV060639

Gene ID

67133

UniProt

Q9D733, A0A0R4J0B9

Accession Number mRNA

NM_025989

Chromosomal Location

7 63.88 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

59.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Gp2

Species

Mouse

Protein ID

NP_080265

Overview

Purified recombinant protein of Mouse glycoprotein 2 (zymogen granule membrane) (Gp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/67133

Uniprot URL

https://www.uniprot.org/uniprot/Q9D733

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_025989

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_080265

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