Gp2 (NM_025989) Mouse Recombinant Protein
Product Specifications
Background
Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participates to the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.[UniProtKB/Swiss-Prot Function]
Synonyms
2310037I18Rik; AV060639
Gene ID
67133
UniProt
Q9D733, A0A0R4J0B9
Accession Number mRNA
NM_025989
Chromosomal Location
7 63.88 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
59.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gp2
Species
Mouse
Protein ID
NP_080265
Overview
Purified recombinant protein of Mouse glycoprotein 2 (zymogen granule membrane) (Gp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67133
Uniprot URL
https://www.uniprot.org/uniprot/Q9D733
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025989
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_080265
Curated Selection
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