Hus1 (NM_008316) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a component of a cell cycle checkpoint complex that causes cell cycle arrest in response to bulky DNA lesions and DNA replication blockage. Together with the proteins Rad9 and Rad1, the encoded protein forms a heterotrimeric complex known as the 9-1-1 complex. Mice lacking the encoded protein develop spontaneous chromosomal abnormalities resulting in embryonic lethality. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Overview
Purified recombinant protein of Mouse HUS1 checkpoint clamp component (Hus1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
MHus1
Gene ID
15574
UniProt
Q8BQY8
Accession Number mRNA
NM_008316
Chromosomal Location
11 5.74 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
32.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Hus1
Species
Mouse
Protein ID
NP_032342
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/15574
Uniprot URL
https://www.uniprot.org/uniprot/Q8BQY8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008316
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032342
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