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Rab11fip3 (NM_001162869) Mouse Recombinant Protein

Product Specifications

Background

Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity) . Also required for the structural integrity of the endosomal recycling compartment during interphase. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse RAB11 family interacting protein 3 (class II) (Rab11fip3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Cart1; D030060O14Rik; mKIAA0665; Rab11-FIP3

Gene ID

215445

UniProt

Q8CHD8

Accession Number mRNA

NM_001162869

Chromosomal Location

17 A3.3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

123.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Rab11fip3

Species

Mouse

Protein ID

NP_001156341

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/215445

Uniprot URL

https://www.uniprot.org/uniprot/Q8CHD8

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001162869

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001156341

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