Rab11fip3 (NM_001162869) Mouse Recombinant Protein
Product Specifications
Background
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity) . Also required for the structural integrity of the endosomal recycling compartment during interphase. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse RAB11 family interacting protein 3 (class II) (Rab11fip3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Cart1; D030060O14Rik; mKIAA0665; Rab11-FIP3
Gene ID
215445
UniProt
Q8CHD8
Accession Number mRNA
NM_001162869
Chromosomal Location
17 A3.3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
123.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rab11fip3
Species
Mouse
Protein ID
NP_001156341
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/215445
Uniprot URL
https://www.uniprot.org/uniprot/Q8CHD8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001162869
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001156341
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