Kars (NM_053092) Mouse Recombinant Protein
Product Specifications
Background
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.[UniProtKB/Swiss-Prot Function]
Synonyms
AA589550; AL024334; AL033315; AL033367; D8Ertd698e; D8Wsu108e; LysRS; mKIAA0070
Gene ID
85305
UniProt
Q99MN1, Q3TIV6
Accession Number mRNA
NM_053092
Chromosomal Location
8 58.27 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
67.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Kars
Species
Mouse
Protein ID
NP_444322
Overview
Purified recombinant protein of Mouse lysyl-tRNA synthetase (Kars), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/85305
Uniprot URL
https://www.uniprot.org/uniprot/Q99MN1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_053092
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_444322
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