Ska3 (NM_198605) Mouse Recombinant Protein
Product Specifications
Background
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse spindle and kinetochore associated complex subunit 3 (Ska3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
F630043A04Rik
Gene ID
219114
UniProt
Q8C263
Accession Number mRNA
NM_198605
Chromosomal Location
14 C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
45.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ska3
Species
Mouse
Protein ID
NP_941007
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/219114
Uniprot URL
https://www.uniprot.org/uniprot/Q8C263
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_198605
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_941007
Curated Selection
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