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Mrc2 (NM_008626) Mouse Recombinant Protein

Selected Variant

PM43980M5

Size: 20 µg

Product Specifications

Background

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse mannose receptor, C type 2 (Mrc2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Endo180; mKIAA0709; uPARAP

Gene ID

17534

UniProt

Q64449, Q14AX9

Accession Number mRNA

NM_008626

Chromosomal Location

11 E1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

167.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Mrc2

Species

Mouse

Protein ID

NP_032652

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/17534

Uniprot URL

https://www.uniprot.org/uniprot/Q64449

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_008626

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_032652

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