Dtx2 (NM_023742) Mouse Recombinant Protein
Product Specifications
Background
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse deltex 2, E3 ubiquitin ligase (Dtx2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
2610524D08Rik; AA408415; AU022494; Deltex2
Gene ID
74198
UniProt
Q8R3P2, A0A0R4IZY1
Accession Number mRNA
NM_023742
Chromosomal Location
5 G2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
67.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dtx2
Species
Mouse
Protein ID
NP_076231
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/74198
Uniprot URL
https://www.uniprot.org/uniprot/Q8R3P2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023742
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_076231
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