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Gja8 (NM_008123) Mouse Recombinant Protein

Product Specifications

Background

Structural component of eye lens gap junctions (PubMed:1325220) . Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity) . Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (PubMed:1325220) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse gap junction protein, alpha 8 (Gja8), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Aey5; Cnx50; Cx50; Lop10

Gene ID

14616

UniProt

P28236, Q548M7

Accession Number mRNA

NM_008123

Chromosomal Location

3

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

49.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Gja8

Species

Mouse

Protein ID

NP_032149

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/14616

Uniprot URL

https://www.uniprot.org/uniprot/P28236

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_008123

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_032149

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