Ppp2r1a (NM_016891) Mouse Recombinant Protein
Product Specifications
Background
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (PubMed:10100624) . Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT (By similarity) . Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse protein phosphatase 2, regulatory subunit A, alpha (Ppp2r1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
6330556D22Rik; PP2A; PR65
Gene ID
51792
UniProt
Q76MZ3
Accession Number mRNA
NM_016891
Chromosomal Location
17 A3.2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
65.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ppp2r1a
Species
Mouse
Protein ID
NP_058587
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51792
Uniprot URL
https://www.uniprot.org/uniprot/Q76MZ3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016891
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_058587
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