Dnase2a (NM_010062) Mouse Recombinant Protein
Selected Variant
PM43927M5
Size: 20 µg
Product Specifications
Background
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse deoxyribonuclease II alpha (Dnase2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Dnase2
Gene ID
13423
UniProt
P56542, Q3UM14
Accession Number mRNA
NM_010062
Chromosomal Location
8 41.31 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
39.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dnase2a
Species
Mouse
Protein ID
NP_034192
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/13423
Uniprot URL
https://www.uniprot.org/uniprot/P56542
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010062
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034192
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