Ctnna2 (NM_009819) Mouse Recombinant Protein
Product Specifications
Background
May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (PubMed:12123610, PubMed:15034585) . Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability (By similarity) . Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (PubMed:12089526) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse catenin (cadherin associated protein), alpha 2 (Ctnna2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI481747; Catna; Catna2; cdf; chp
Gene ID
12386
UniProt
Q61301
Accession Number mRNA
NM_009819
Chromosomal Location
6 33.54 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
105.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ctnna2
Species
Mouse
Protein ID
NP_033949
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12386
Uniprot URL
https://www.uniprot.org/uniprot/Q61301
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009819
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033949
Curated Selection
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