Prex2 (NM_029525) Mouse Recombinant Protein
Product Specifications
Background
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 2 (Prex2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
6230420N16Rik; AI316880; AI553603; C030045D06Rik; D430013K02; Depdc2; P-Rex2
Gene ID
109294
UniProt
Q3LAC4
Accession Number mRNA
NM_029525
Chromosomal Location
1 A2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
181.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Prex2
Species
Mouse
Protein ID
NP_083801
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/109294
Uniprot URL
https://www.uniprot.org/uniprot/Q3LAC4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_029525
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_083801
Curated Selection
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