Sco1 (NM_001040026) Mouse Recombinant Protein

Product Specifications

Background

Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2) . Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu (A) site on MT-CO2/COX2 (By similarity) . Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (PubMed:25683716, PubMed:28973536) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse SCO1 cytochrome c oxidase assembly protein (Sco1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2610001C07Rik; D11Bwg1310e

Gene ID

52892

UniProt

Q5SUC9

Accession Number mRNA

NM_001040026

Chromosomal Location

11 40.59 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

31.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.