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Hecw2 (NM_172655) Mouse Recombinant Protein

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (Hecw2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

A730039N16Rik; D030049F17Rik; Gm971; mKIAA1301; Nedl2

Gene ID

329152

UniProt

Q6I6G8, A3KPB7

Accession Number mRNA

NM_172655

Chromosomal Location

1 C1.1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

33.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Hecw2

Species

Mouse

Protein ID

NP_766243

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/329152

Uniprot URL

https://www.uniprot.org/uniprot/Q6I6G8

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_172655

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_766243

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