Dguok (NM_013764) Mouse Recombinant Protein
Product Specifications
Background
Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse deoxyguanosine kinase (Dguok), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
DGK; dGK1; dGK2; dGK3
Gene ID
27369
UniProt
Q9QX60
Accession Number mRNA
NM_013764
Chromosomal Location
6 35.94 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
32.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dguok
Species
Mouse
Protein ID
NP_038792
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27369
Uniprot URL
https://www.uniprot.org/uniprot/Q9QX60
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013764
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_038792
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