Plce1 (NM_019588) Mouse Recombinant Protein
Product Specifications
Background
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.[UniProtKB/Swiss-Prot Function]
Synonyms
4933403A21Rik; mKIAA1516; Plce; PLCepsilon
Gene ID
74055
UniProt
Q8K4S1
Accession Number mRNA
NM_019588
Chromosomal Location
19 C3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
255 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Plce1
Species
Mouse
Protein ID
NP_062534
Overview
Purified recombinant protein of Mouse phospholipase C, epsilon 1 (Plce1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/74055
Uniprot URL
https://www.uniprot.org/uniprot/Q8K4S1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019588
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062534
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