Pde3b (NM_011055) Mouse Recombinant Protein
Product Specifications
Background
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
9830102A01Rik; AI847709
Gene ID
18576
UniProt
Q61409, E9QLQ3, Q3UQ25
Accession Number mRNA
NM_011055
Chromosomal Location
7 59.46 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
122.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pde3b
Species
Mouse
Protein ID
NP_035185
Overview
Purified recombinant protein of Mouse phosphodiesterase 3B, cGMP-inhibited (Pde3b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/18576
Uniprot URL
https://www.uniprot.org/uniprot/Q61409
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011055
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035185
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