Stim2 (NM_001081103) Mouse Recombinant Protein
Product Specifications
Background
Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores. Functions as a highly sensitive Ca (2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca (2+) -influx. Regulates basal cytosolic and endoplasmic reticulum Ca (2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca (2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca (2+) release-activated Ca (2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca (2+) influx (By similarity) .[UniProtKB/Swiss-Prot Function]
Gene ID
116873
UniProt
P83093, A5CVE4
Accession Number mRNA
NM_001081103
Chromosomal Location
5 29.69 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
84.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Stim2
Species
Mouse
Protein ID
NP_001074572
Overview
Purified recombinant protein of Mouse stromal interaction molecule 2 (Stim2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/116873
Uniprot URL
https://www.uniprot.org/uniprot/P83093
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001081103
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001074572
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