Rgs20 (NM_001177795) Mouse Recombinant Protein

Product Specifications

Background

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G (z) -alpha and G (alpha) -i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G (z) -alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse regulator of G-protein signaling 20 (Rgs20), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

2900073E09Rik; Rgsz1

Gene ID

58175

UniProt

Q8C5J7, E9Q720

Accession Number mRNA

NM_001177795

Chromosomal Location

1 A1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

41.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.