Brk1 (NM_133937) Mouse Recombinant Protein
Product Specifications
Background
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity) . As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse BRICK1, SCAR/WAVE actin-nucleating complex subunit (Brk1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
6720456B07Rik; AW011779
Gene ID
101314
UniProt
Q91VR8
Accession Number mRNA
NM_133937
Chromosomal Location
6 E3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
9.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Brk1
Species
Mouse
Protein ID
NP_598698
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/101314
Uniprot URL
https://www.uniprot.org/uniprot/Q91VR8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133937
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_598698
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