Fmo3 (NM_008030) Mouse Recombinant Protein
Product Specifications
Background
Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse flavin containing monooxygenase 3 (Fmo3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AW111792
Gene ID
14262
UniProt
P97501, Q3UEN4, Q8C7J1
Accession Number mRNA
NM_008030
Chromosomal Location
1 70.34 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
61 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Fmo3
Species
Mouse
Protein ID
NP_032056
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14262
Uniprot URL
https://www.uniprot.org/uniprot/P97501
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008030
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032056
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